Gene expression analysis is a cornerstone of molecular biology, providing critical insights into cellular function, disease mechanisms, and therapeutic targets. Central to this process is reverse transcriptase, the enzyme that enables reverse transcription, converting RNA molecules into complementary DNA (cDNA). This technology has fundamentally transformed the way researchers study gene activity. The Role of Reverse […]The postHow Reverse Transcriptase Has Revolutionized Gene Expression Analysisappeared first onJ L I Blog. ...继续阅读 (21)

[social4i size="small" align="align-left"][This article was first published onpacha.dev/blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.If this post is useful to you I kindly ask a minimal donation onBuy Me a Coffee. It shall be used to continue my Open Source efforts. The full explanation is here:A Personal Message from an Open Source Contributor.You can send me questions for the blog usingthis formand subscribe to receive an email when there is a new ...继续阅读 (34)

[social4i size="small" align="align-left"][This article was first published onpacha.dev/blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.If this post is useful to you I kindly ask a minimal donation onBuy Me a Coffee. It shall be used to continue my Open Source efforts. The full explanation is here:A Personal Message from an Open Source Contributor.You can send me questions for the blog usingthis formand subscribe to receive an email when there is a new ...继续阅读 (32)

[social4i size="small" align="align-left"][This article was first published onpacha.dev/blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.If this post is useful to you I kindly ask a minimal donation onBuy Me a Coffee. It shall be used to continue my Open Source efforts. The full explanation is here:A Personal Message from an Open Source Contributor.You can send me questions for the blog usingthis formand subscribe to receive an email when there is a new ...继续阅读 (33)

[social4i size="small" align="align-left"][This article was first published onpharmaverse blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.------------- typical setup ---------------------------- post begins here ---------------Clinical trials are a crucial component of the pharmaceutical industry, providing the evidence needed to demonstrate the safety, efficacy, and overall benefit of new drugs or treatments.Clinical trials reporting, a detailed proce ...继续阅读 (29)

[social4i size="small" align="align-left"][This article was first published onBluecology blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Paper in a prompt creating a first draft in one prompt**It was a rather long promptI wanted to see if I could get an AI agent to complete a first draft of a paper, including data analysis, searching for references on the web and writing a complete draft.I used the Roo Code agent software with the Claude Sonnet 4.0 lar ...继续阅读 (34)

[social4i size="small" align="align-left"][This article was first published onpacha.dev/blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.If this post is useful to you I kindly ask a minimal donation onBuy Me a Coffee. It shall be used to continue my Open Source efforts. The full explanation is here:A Personal Message from an Open Source Contributor.You can send me questions for the blog usingthis formand subscribe to receive an email when there is a new ...继续阅读 (26)

[social4i size="small" align="align-left"][This article was first published onrOpenSci - open tools for open science, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.We have developed a prototype dashboard which aims to help organizations maintain complex systems of inter-dependent software components. Our initialprototype organizational dashboardprovides insights into code contributors, their repositories, and maintenance status and needs. The prototype das ...继续阅读 (29)

9 月 5 日这一天，Anthropic 在官网发布了一则消息：立即停止 Claude 向中国资本控股企业提供服务。所谓“控股”，指的是持股比例超过 50% 的企业，这一政策覆盖的可不仅仅是大陆公司，事实上大陆公司本身也用不了。这个策略同时包括那些在境外注册，但有中国资本或股东背景的公司和组织。目前看起来，Claude 这条路在中国企业这里彻底断掉了。AI 的地缘政治过去二十年，互联网科技产品大多强调“全球化”。硅谷的产品可以在北京、东京、柏林同时使用，哪怕偶尔有审查或功能阉割，底层的技术逻辑还是相通的。但到了 AI 时代，这条路越来越窄了。先是芯片，后是软件。Anthropic 在公告中说，这项措施是为了“应对法律、监管与国家安全风险”。换句话说，AI 已经被当作战略资源。和石油、芯片一样，AI 模型不再是单纯的商业工具，早就被嵌入到大国博弈的棋盘里。这一点在 GPT-4 之后已经很明显。美国政府把最先进的 AI 模型看作“国防资产”，严格控制其出口与使用范围。现在 Anthropic 的决定只是把这种控制明确落地到商业规则中：你是谁、你后面是谁，这决定了你能不能用 Claude。有意思的是，Anthropic 并非只针对中国，公告里明确提到，这一政策同样适用于美国认定的“对手国家”（adversarial nations），比如俄罗斯啊、伊朗啊、朝鲜等等。blacklist，在 ...继续阅读 (34)

[social4i size="small" align="align-left"][This article was first published onR – TomazTsql, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.This one is named, yes, you guessed it, after Markov chains.The babbler is there to connotate the simplicity of useless R function.It’s simple calculation of probability of words chaining and drawing the multiple times appeared chained words reminds of markov chain (although this is not it!).The gist is is tokenization ...继续阅读 (34)

[social4i size="small" align="align-left"][This article was first published onpacha.dev/blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.If this post is useful to you I kindly ask a minimal donation onBuy Me a Coffee. It shall be used to continue my Open Source efforts. The full explanation is here:A Personal Message from an Open Source Contributor.You can send me questions for the blog usingthis formand subscribe to receive an email when there is a new ...继续阅读 (32)

[social4i size="small" align="align-left"][This article was first published onjakub::sobolewski, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Your Shiny app has business logic scattered everywhere.Testing it feels impossible. Every time you touch one piece, three others break. Dependencies tangle together like headphone cables in your pocket.There’s a cleaner way.Interfaces Define What, Not HowR6 interfaces let you bundle concepts together without locking ...继续阅读 (30)

[social4i size="small" align="align-left"][This article was first published onThe Jumping Rivers Blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.AtJumping Rivers, we combine engineering, automation, and analytics to streamline your data workflows and make them more efficient. We take care of the tasks you don’t have the time or capacity for, improve processes you might not even know could be optimised, and work alongside your team to make your data and ...继续阅读 (28)

[social4i size="small" align="align-left"][This article was first published onR-posts.com, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Join our workshop titled From a slow analysis script to a fast and structured program in R, which is a part of our workshops for Ukraine series!Here’s some more info:Title:From a slow analysis script to a fast and structured program in RDate:Thursday, October 9th, 18:00 – 20:00 CEST (Rome, Berlin, Paris timezone)Speaker:J ...继续阅读 (30)

[social4i size="small" align="align-left"][This article was first published onGetting Genetics Done, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Reposted from the original athttps://blog.stephenturner.us/p/development-environment-portable-reproducible.You upgrade your old Intel Macbook Pro for a new M4 MBP. You’re setting up a new cloud VM on AWS after migrating away from GCP. You get an account on your institution’s new HPC. You have everythingjust so ...继续阅读 (27)

[social4i size="small" align="align-left"][This article was first published onGetting Genetics Done, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Reposted from the original athttps://blog.stephenturner.us/p/codex-positron.Last month I wrote about agentic coding in Positron using Positron assistant, which uses the Claude API on the back end.Positron Assistant: GitHub Copilot and Claude-Powered Agentic Coding in RStephen Turner·Jul 16Read full storyYesterda ...继续阅读 (26)

[social4i size="small" align="align-left"][This article was first published onGetting Genetics Done, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Reposted from the original athttps://blog.stephenturner.us/p/positron-assistant-copilot-chat-agentI have a little hobby project I’m working on and I wanted to use the opportunity to fully make the switch toPositronfrom RStudio. I used Positron here and there when it first came out, but now that it’s out of beta ...继续阅读 (27)

[social4i size="small" align="align-left"][This article was first published onDataGeeek, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.The French government is planning to hold a confidence vote on Prime Minister François Bayrou’s fiscal plan.If a coalition of opposition parties votes against the government, as is widely expected, Bayrou will have to submit his resignation to French President Emmanuel Macron.This could cause a fall to the middle band for t ...继续阅读 (30)

[social4i size="small" align="align-left"][This article was first published onT. Moudiki's Webpage - R, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Inhttps://github.com/thierrymoudiki/2025-09-05-transfer-learning-ridge2f, I pretrainahead::ridge2f(alsoavailable Python) on 1000 synthetic stock returns using Bayesian Optimization, and test its performance (coverage rate andWinkler scorefor now) on real market data.Here’s how I obtained the synthetic stock r ...继续阅读 (28)

[social4i size="small" align="align-left"][This article was first published onT. Moudiki's Webpage - R, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Inhttps://github.com/thierrymoudiki/2025-09-05-transfer-learning-ridge2f, I pretrainahead::ridge2f(alsoavailable Python) on 1000 synthetic stock returns using Bayesian Optimization, and test its performance on real market data.In order to reproduce results fromhttps://github.com/thierrymoudiki/2025-09-05-tran ...继续阅读 (27)

[social4i size="small" align="align-left"][This article was first published onR/exams, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Canvas quizzes can be created with exams2canvas in R/exams and then imported and managed in Canvas using the R package vvcanvas.OverviewThis tutorial illustrates how to useR/examsin combination withvvcanvasfor creating and managing quizzes forCanvas.exams2canvas()has long been available in R/exams and allows to create QTI zip ...继续阅读 (25)

[social4i size="small" align="align-left"][This article was first published onOnline College Math Teacher, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Davey Johnson, former baseball player and manager, recently passed away. He was notable in the math and data analysis world for being an early proponent of sabermetrics, the use of statistical analysis of baseball to provide insights into player and team performance, long before the 2003 Moneyball book an ...继续阅读 (28)

[social4i size="small" align="align-left"][This article was first published onpacha.dev/blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.If this post is useful to you I kindly ask a minimal donation onBuy Me a Coffee. It shall be used to continue my Open Source efforts. The full explanation is here:A Personal Message from an Open Source Contributor.You can send me questions for the blog usingthis formand subscribe to receive an email when there is a new ...继续阅读 (30)

[social4i size="small" align="align-left"][This article was first published onr on Everyday Is A School Day, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Ever wondered how DNA alignment actually works under the hood?We coded the Needleman-Wunsch algorithm from scratch, working through scoring matrices by hand with simple examples like “CAT” vs “CT” before testing on real E. coli sequences. Pretty neat to see the magic happen!MotivationsWe’ve looked atdete ...继续阅读 (27)

[social4i size="small" align="align-left"][This article was first published ontshafer.com, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.I’m going to be in-person atposit::conf 2025in Atlanta, giving a talk about how fundamental R development practices have made model governance (which I’m defining as all the stuff that happensafterinitial deployment) better forusover the last few years.As the talk has come together, it’s turning out higher-level than the ...继续阅读 (28)

[social4i size="small" align="align-left"][This article was first published onfree range statistics - R, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Iwrote a reviewlast week ofStruggle, reform, boom and bust: an economic history of Papua New Guinea since independenceby Stephen Howes and others. The review was published in the Devpolicy Blog at The Australian National University’s Development Policy Centre in the Crawford School of Public Policy. My post ...继续阅读 (28)

[social4i size="small" align="align-left"][This article was first published onDataGeeek, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Goldman Sachs stated that if the FED’s reputation suffers, and investors move only a small portion of their bond holdings into gold, the price of gold could rise to nearly $5,000 an ounce.But at least now, the ensemble model indicates that gold prices are in an overbought zone.Source code:library(tidymodels) library(tidyver ...继续阅读 (24)

[social4i size="small" align="align-left"][This article was first published onpacha.dev/blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Because of delays with my scholarship payment, if this post is useful to you I kindly ask a minimal donation onBuy Me a Coffee. It shall be used to continue my Open Source efforts. The full explanation is here:A Personal Message from an Open Source Contributor.You can send me questions for the blog usingthis formand su ...继续阅读 (26)

[social4i size="small" align="align-left"][This article was first published onpacha.dev/blog, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.Because of delays with my scholarship payment, if this post is useful to you I kindly ask a minimal donation onBuy Me a Coffee. It shall be used to continue my Open Source efforts. The full explanation is here:A Personal Message from an Open Source Contributor.You can send me questions for the blog usingthis formand su ...继续阅读 (25)

[social4i size="small" align="align-left"][This article was first published onT. Moudiki's Webpage - R, and kindly contributed toR-bloggers]. (You can report issue about the content on this pagehere)Want to share your content on R-bloggers?click hereif you have a blog, orhereif you don't.I’m supposed to present a poster for this publication of minehttps://proceedings.mlr.press/v266/moudiki25a.htmlin London in a few days atCOPA CONFERENCE 2025but it’s nearly impossible. Could anybody guess why? Hint in the links below.Publications related to the poster (in R and Python):https://thierrymoudiki. ...继续阅读 (28)